Knowledge Management Essay Example | Topics and Well Written Essays - 1750 words

Knowledge Management - Essay Example There are no doubts in the fact that the business environment of this globalised world has been changed radically due to the revolution that the world has witnessed in information technology. The marketplace has become increasingly competitive, competition is becoming cutthroat, suppliers have become intelligent, customers have become more demanding, and substitutes are increasing in number. General Electric is the only corporation which has been able to survive amongst the top 10 companies that appeared on the Dow Jones Index in 1900. Furthermore, only four out of the Fortune 500 companies of 1900 were able to make it to the 21st century (Davenport & Prusak, 2000, pp. 20-21). It appears that the marketplace is now operating on the principle that used to govern the earliest human societies, â€Å"survival of the fittest†. Alice Carol once wrote something which perfectly depicts the business environment of today. â€Å"Now here, you see, it takes all the running you can do to keep you in the same place. If you want to get somewhere else, you must run at least twice as fast as that† (Rao, 2005, p. 36). In order to ensure that organisations are â€Å"running twice as fast†, they have come up with a variety of procedures and techniques to improve their profitability, productivity and exploit all possible opportunities. Knowledge management is amongst one of them. The raw material, which was made available to them, included steel drums, logs, pontoons, and some rope. However, the real catch was that these managers, from different countries, were not allowed to communicate with uttering a single word from their mouth (Voelpel & Han, 2005, pp. 55-56). Therefore, the communication was talking place with the help of diagrams and sentences on the flip charts.

Drug Discovery Processes

Drug Discovery Processes Introduction Chemistry is not merely a science of making observations in order to better understand nature. Chemistry, as the science of matter and its transformation, plays a central role in bridging between physics, material sciences and life sciences. Our science is creative and productive, generating substances and materials of very high value from almost nothing. In view of its significance, chemical synthesis demands the highest level of scientific/technological creativity and insight to explore its limitless possibilities. Chemical synthesis must pursue the goal of practical elegance; it must be logically elegant and at the same time technologically practical. We must manufacture useful compounds in an economical, energy-efficient, resource-preserving, and environmentally benign way(add ref impo-01). To maintain our current standard of living and to improve quality of life, society has come to depend on the products of chemical industry. The last century has been highly productive in this aspect as it emerges in development in pharmaceutical development, water treatment, material science, polymers, agriculture pesticides and fungicides, detergents, petroleum additives and so forth. Pharmaceutical development plays a vital role as various drugs that are developed have helped in the eradication of many infectious diseases. Although there are certain diseases that have still not found any resistance towards drugs but even though a lot of work is still being carried out on it. Research in the field of pharmaceutical has its most important task in the development of new and better drugs and their successful introduction into clinical practice. â€Å"Medicinal chemistry remains a challenging science which provides profound satisfaction to its practitioners. It intrigues those of us who like to solve problems posed by nature. It verges increasingly on biochemistry and on all the physical, genetic and chemical riddles in animal physiology which bear on medicine. Medicinal chemists have a chance to participate in the fundamentals of prevention, therapy and understanding of diseases and thereby to contribute to a healthier and happier life.† ALFRED BURGER 3   Importance of a Drug: A drug is any chemical or biological substance, synthetic or non-synthetic, that when taken into the organism’s body, will in some way after the functions of that organism’s. This broad definition can be made by including such substances as food. However more strict applications of the word prevail in everyday life. In these cases the word â€Å"drug† is usually used to refer specifically to medicine, vitamins, entheogenic sacraments, consciousness expanding or recreational drugs. Many natural substances such as beers, wine, and some mushrooms, blur the line between food and drugs, when ingested they affect the functioning of both mind and body. The word â€Å"drug† is etymologically derived from the Dutch/Low German word â€Å"droog† which means â€Å"dry†, since in the past; most drugs were dried plant parts. Drugs are usually distinguished from endogenous biochemical by being introduced from outside the organism. For example, insulin is a hormone that is synthesized in the body; it is called a hormone when it is synthesized by the pancreas inside the body, but if it is introduced into the body from outside, it is called a drug. The role played by organic chemistry in the pharmaceutical industry continues to be one of the main drivers in the drug discovery process. However, the precise nature of that role is undergoing a visible change, not only because of the new synthetic methods and technologies now available to the synthetic and medicinal chemist, but also in several key areas, particularly in drug metabolism and chemical toxicology, as chemists deal with the ever more rapid turnaround of testing data that influences their day-to-day decisions. Numerous changes are now occurring in the pharmaceutical industry, not just in the way that the industry is perceived, but also in the rapid expansion of biomedical and scientific knowledge, which affects the way science is practiced in the industry. The recent changes that have occurred in scientific advances are due to the new synthetic techniques and new technologies for rational drug design, combinatorial chemistry, automated synthesis, and compound purification and identification. In addition, with the advent of high-throughput screening (HTS), we are now faced with many targets being screened and many hits being evaluated. However, success in this arena still requires skilled medicinal chemists making the correct choices, often with insight gleaned from interactions with computational chemists and structural biologists, about which â€Å"hits† are likely to play out as true â€Å"lead† structures that will meet the plethora of hurdles that any drug candidate must surmount. It is the mission of pharmaceutical research companies to take the path from understanding a disease to bringing a safe and effective new treatment to patients. Scientists work to piece together the basic causes of disease at the level of genes, proteins and cells. Out of this understanding emerge â€Å"targets,† which potential new drugs might be able to affect. Researchers work to validate these targets, discover the right molecule (potential drug) to interact with the target chosen, test the new compound in the lab and clinic for safety and efficacy and gain approval and get the new drug into the hands of doctors and patients. The drug discovery process goes through following sequences for the development of particular drug4. Pre-discovery (Understand the disease) Before any potential new medicine can be discovered, scientists work to understand the disease to be treated as well as possible, and to unravel the underlying cause of the condition. They try to understand how the genes are altered, how that affects the proteins they encode and how those proteins interact with each other in living cells, how those affected cells change the specific tissue they are in and finally how the disease affects the entire patient. This knowledge is the basis for treating the problem. Researchers from government, academia and industry all contribute to this knowledge base. However, even with new tools and insights, this research takes many years of work and, too often, leads to frustrating dead ends. And even if the research is successful, it will take many more years of work to turn this basic understanding of what causes a disease into a new treatment. Target Identification (Choose a molecule to target with a drug) Once they have enough understanding of the underlying cause of a disease pharmaceutical researchers select a â€Å"target† for a potential new medicine. A target is generally a single molecule, such as a gene or protein, which is involved in a particular disease. Even at this early stage in drug discovery it is critical that researchers pick a target that is â€Å"drugable,† i.e., one that can potentially interact with and be affected by a drug molecule. Target Validation (Test the target and confirm its role in the disease) After choosing a potential target, scientists must show that it actually is involved in the disease and can be acted upon by a drug. Target validation is crucial to help scientists avoid research paths that look promising, but ultimately lead to dead ends. Researchers demonstrate that a particular target is relevant to the disease being studied through complicated experiments in both living cells and in animal models of disease. Drug Discovery (Find a promising molecule that could become a drug) Armed with their understanding of the disease, scientists are ready to begin looking for a drug. They search for a molecule, or â€Å"lead compound,† that may act on their target to alter the disease course. If successful over long odds and years of testing, the lead compound can ultimately become a new medicine. There are a few ways to find a lead compound: Nature: Scientists usually have turned to nature for find interesting compounds for fighting against diseases. Bacteria found in soil and mouldy plants both led to important new treatments. Nature still offers many useful substances, but now there are other ways to approach drug discovery. De novo: Thanks to advances in chemistry, scientists can also create molecules from scratch. They can use sophisticated computer modelling to predict what type of molecule may work. High-throughput Screening: This process is the most common way that leads are usually found. Advances in robotics and computational power allow researchers to test hundreds of thousands of compounds against the target to identify any that might be promising. Based on the results, several lead compounds are usually selected for further study. Biotechnology: Scientists can also genetically engineer living systems to produce disease-fighting biological molecules. Early Safety Tests(Perform initial tests on promising compounds) Lead compounds go through a series of tests to provide an early assessment of the safety of the lead compound. Scientists test Absorption, Distribution, Metabolism, Excretion and Toxicological (ADME/Tox) properties, or â€Å"pharmacokinetics,† of each lead. These studies help researchers prioritize lead compounds early in the discovery process. ADME/Tox studies are performed in living cells, in animals via computational models. Lead Optimization(Alter the structure of lead candidates to improve properties) Lead compounds that survive the initial screening are then optimized, or altered to make them more effective and safer. By changing the structure of a compound, scientists can give it different properties. For example, they can make it less likely to interact with other chemical pathways in the body, thus reducing the potential for side effects. Hundreds of different variations or â€Å"analogues† of the initial leads are made and tested. Teams of biologists and chemists work together closely: The biologists test the effects of analogues on biological systems while the chemists take this information to make additional alterations that are then retested by the biologists. The resulting compound is the candidate drug. Even at this early stage, researchers begin to think about how the drug will be made, considering formulation (the recipe for making a drug, including inactive ingredients used to hold it together and allow it to dissolve at the right time), delivery mechanism (the way the drug is taken – by mouth, injection, inhaler) and large-scale manufacturing (how you make the drug in large quantities). Preclinical Testing(Lab and animal testing to determine if the drug is safe enough for human testing) With one or more optimized compounds in hand, researchers turn their attention to testing them extensively to determine if they should move on to testing in humans. Scientists carry out in vitro and in vivo tests. In vitro tests are experiments conducted in the lab, usually carried out in test tubes and beakers (â€Å"vitro† is â€Å"glass† in Latin) and in vivo studies are those in living cell cultures and animal models (â€Å"vivo† is â€Å"life† in Latin). Scientists try to understand how the drug works and what its safety profile looks like. The U.S. Food and Drug Administration (FDA) require extremely thorough testing before the candidate drug can be studied in humans. During this stage researchers also must work out how to make large enough quantities of the drug for clinical trials. Techniques for making a drug in the lab on a small scale do not translate easily to larger production. This is the first scale up. The drug will need to be scaled up eve n more if it is approved for use in the general patient population. At the end of several years of intensive work, the discovery phase concludes. After starting with approximately 5,000 to 10,000 compounds, scientists now have winnowed the group down to between one and five molecules, â€Å"candidate drugs,† which will be studied in clinical trials. The drugs that are being currently used for curing human ailments mainly comprise of several natural products having complex structures. These are derived from terrestrial micro-organisms, plants and animals. The synthetic analogues of the above or other synthetic compounds that are totally non-natural also serve as drugs. A survey of literature reveals that â€Å"HETEROCYCLES† have been increasingly important not only in the field of medicinal world but also in the agriculture. The chemistry of the heterocyclic compounds is as logical as that of aliphatic or aromatic compounds. This study is of great interest both from the theoretical as well as practical stand point. Heterocyclic compounds are the organic substrates that contain a cyclic structure bearing atoms like nitrogen, oxygen or sulfur in addition to carbon atom as the part of their ring. The cyclic part (from Greek kyklos, meaning circle) of heterocycle indicates that at least one ring structure is present in such a compound and the prefix hetero (from Greek heteros, meaning other or different) refers to non-carbon atom in the ring. The cyclic part of the heterocycle indicates that at least one ring structure is cyclic organic compound that incorporate at least one hetero atom in the rings like cyclopropane or benzene. The presence of the heteroatom gives heterocyclic compounds many significant physical and chemical properties that are usually distinct from those of all carbon-ring analogues. These structures may comprise of either simple aromatic rings or non-aromatic ring. The chemistry of heterocyclic compounds is one of the most interesting and intriguing branch of the organic chemistry which is of equal interests for its theoretical implications, for the diversity of its synthetic procedures and for the physiological and industrial significances.1-2 The variety of heterocyclic compounds is enormous, their chemistry is complex and synthesizing them requires great skill. Among large number of heterocycles found in nature nitrogen heterocycles are most abundant than those containing oxygen or sulphur owing to their wide distribution in nucleic acid instance and involvement in almost every physiological process of plants and animals. It is well known that a number of heterocyclic compounds containing nitrogen, oxygen and sulphur exhibit a wide variety of biological activities. The majority of pharmaceutical products that mimic natural products with biological activity are heterocyclic in nature3 and are of great importance to life because their structural subunits exist in many natural products such as vitamins, hormones, antibiotics and pigments.4,5 Besides the vast distribution of heterocycles in natural products, these substrates are also the major components of biological molecules such as DNA and RNA, in the form of pyrimidine and purine bases. The enzymes possess purely protein structures and the coenzymes incorporate non-amino acid moieties, most of them are aromatic nitrogen heterocycles. Porphyrins8-10 are the backbone of many major compounds and some of their derivatives are fundamental to life, such as heme11 derivatives in blood and chlorophyll is essential for photosynthesis. The heme group of the oxygen-carrying protein-hemoglobin and related compounds such as myoglobin; the chlorophyll, which are the light-gathering pigments of green plants and other photosynthetic organisms, and vitamin B12 are all formed from four pyrrole units joined in a larger ring system known as a porphyrin, such as that of chlorophyll a 1.9 and chlorophyll b 1.10. Many vitamins13 like folic acid 1.12, vitamin B5, nicotinic acid 1.13, nicotinamide 1.14, vitamin B6 pyridoxine 1.15, pyridoxal 1.16, and pyridoxamine 1.17 are well known heterocyclic compounds. Psoralen consists of coumarin fused with furan rings, is used in treatment for skin problems and it shows considerable clinical efficacy.14 Cinchona bark15 has been used for several hundred years for the treatment of malaria where quinine 1.21 is the active heterocyclic component. Caffeine (1,3,7-trimethylxanthine) 1.22 obtained commercially from methylation of xanthine with methyl chloride or dimethylsulphate and alkali, is the major stimulant in tea and coffee. Natural products containing heterocyclic compounds such as alkaloids and glycosides have been used since old age, as remedial agents. Febrifagl alkaloid from ancient Chinese drug, Chang Shan, reserpine from Indian rouwopifia, Curen alkaloid from arrow poison, codenine, j-tropine and strychnine are all examples of heterocyclic compounds. Many alkaloids37 contain a pyridine or piperidine ring structure, among them nicotine 1.55, the main alkaloid constituent of tobacco, is based on the five membered pyrrolidine and six membered pyridine structures and piperine 1.56 which is one of the sharp-tasting constituents of white and black pepper and it is obtained from the plant species piper nigrum. The benzimidazole derivatives 1.64-1.68 having antifungal, antibacterial, anti-inflammatory and analgesics properties have been successfully prepared.41 Imidazo[1,2-a]pyridines have attracted much attention since the beginning of the last century. Due to their important biological activity, they have, in recent years, been broadly investigated and utilized in the pharmaceutical industry. They are also used in bioimaging probes and molecular recognition because of their structural characters.1 In addition, the imidazo[1,2 -a]pyridine scaffolds have been found to be the core structure of many natural products and drugs such as zolpidem, alpidem, saripidem, tenatoprazole, olprinone, and DS-1.2,3 (3)Zhuan Fei, Yan-ping Zhu ⇑, Mei-cai Liu, Feng-cheng Jia, An-xin Wu Tetrahedron Letters 54 (2013) 1222–1226 (imidazo-5 in reference folder) Heterocyclic compounds are obtainable by the following methods. a. Isolation from natural sources, i.e. alkaloids, amino acids, indigo dyes etc. b. Degradation of natural products i.e. acridine, furfural, indol, pyridine, quinoline, thiophene etc. c. Synthesis: Synthesis methods for obtaining heterocyclic compounds may be divided into ring closer reactions, addition reaction and replacement reaction. Cyclisation is usually accomplished by elimination of some small molecules such as water or ammonia from chain of suitable length. Heterocyclic compounds have a great applicability as drugs because, a. They have a specific chemical reactivity. b. They resemble essential metabolism and can provide false synthons in biosynthetic process. Aims and objectives: Taking in view the applicability of heterocyclic compounds, we have undertaken the preparation of heterocycles bearing triazole and pyrimidines nucleus. The placements of a wide variety of substituents of these nuclei have been designed in order to evaluate the synthesized products for their pharmacological profile against several strains of bacteria and fungi and tuberculosis. During the course of our research work, looking to the application of heterocyclic compounds, several entities have been designed, generated and characterized using spectral studies. The details are as under. To synthesize several bioactive derivatives of benzo[d]imidazo and its Schiff’s base and dihydro pyrazolothiazoles. To generate triazolo [1,5-a]pyrimidine derivatives. To synthesize imidazo [1,2-a]pyridine by Green Synthesis and develop their Mannich base. To check purity of all synthesized compounds using thin layer chromatography. To characterize these synthesized products for structure elucidation using various spectroscopic techniques like IR, 1H and 13C NMR and mass spectral studies. To grow single crystal of the synthesized compounds and study there X-ray crystallography for establishment of the structure. To evaluate these new synthesized products for better drug potential against different strains of bacteria and fungi.

Technological Diversification of College Students Essay -- Technology

Technological Diversification of College Students Writing takes on many faces, from personal stories to make believe places. College writing however, has a completely different designation. Furthermore, computer intensive college writing looks further into the depths of writing, focusing on technology and the writers behind the computer screens. With the unbound horizons of technology, students are exposed to a vast amount of culture, much more than the traditional pen and paper courses. Computer intensive college writing courses teardown roadblocks, allowing students to become aware of surrounding cultures, therefore diversifying their minds while exposing them to the current technology. Exposure to technology is key not only to succeed in a computer intensive college writing class, but also to succeed in the future. Technology has become more prevalent in today's society. From cell phones in purses, to email stations located all around college campuses. Technology is cropping up in business and industry; those without the skills to be able to interface with technology are pushed aside. As Kathy Camper wrote in her article "A Note from the Future," published in Wired magazine, "How do you think, see a system analysis job and I don't even no enough numbers to punch in and get inside the door" (Camper). This excerpt from Camper's article displays a prime example of a person who is shunned outside because lack of technological skills. Computers are the gateway to diversity, opening the doors to worlds thousands of miles away. These gateways allow students to understand and respect opinions not originally of their own. Maxine Hairston, a professor of rhetoric and composition at the University of Texas, holds views of how... ...hink, to generate ideas, and to present themselves effectively to the university and the community" (Hairston). Not only will the ideas learned by the students help them succeed in other courses, but also it will carry on with them into the future. From advancements in technology to the idea of cultural acceptance, college writing class is the starting point of creating diversified thinking and problem solving. Works Cited Camper, Kathy. "A Note from the Future." Wired. January 1995. http://www.wired.com/wired/archive/3.01/camper.if.html. Calice, Corrine, Marshall Kitchens, and Richard Marback. "An Introduction to Reading, Thinking, and Writing in a Digital World." Writing Cultures in a Digital Age. Boston: Houghton-Mifflin, 2001. Hairston, Maxine. "Diversity, Ideology, and Teaching Writing." College Compostion and Communication. May 1992: 179-195.

Taxation Fte

8/3/2011 The  Economics  of  Taxation Lecture  11:  Taxation  and  Business  Valuation:  FTE  approach International  Accounting International Accounting and Taxation Master  of Science  (MSc) University  of Liechtenstein,  Vaduz Dr. Tanja  Kirn D T j Ki Chair for Tax  Management  and the Laws  of International  and Liechtenstein  Taxation Institute  for Financial  Services University  of Liechtenstein,  Vaduz The  Economics  of  Taxation Taxation  and  Business  Valuation:  FTE  approach Exercise Suppose  Lucent  Technologies  has  an  equity  cost  of  capital  of  10%,  market   capitalization  of  $10.   billion,  and  an  enterprise  value  of  $14. 4  billion. Suppose   p $ , p $ pp Lucent’s  debt  cost  of  capital  is  6. 1%  and  its  marginal  tax  rate  is  35%. a. What  is  Lucent’s  WACC? b. If  Lucent  maintain s  a  constant  debt? equity  ratio,  what  is  the  value  of  a  project  with   average  risk  and  the  following  expected  free  cash  flows? c. If  Lucent  maintains  its  debt? equity  ratio,  what  is  the  debt  capacity  of  the  project  in   part  (b)? part (b)? d. What  is  the  free  cash  flow  to  equity  for  this  project? e. What  is  its  NPV  computed  using  the  FTE  method? How  does  it  compare  with  the   NPV  based  on  the  WACC  method?  ©Ã‚  2011  Dr. Tanja  Kirn  Ã¢â‚¬â€œ University  of  Liechtenstein  Ã¢â‚¬â€œ Vaduz 2 1 8/3/2011 The  Economics  of  Taxation Taxation  and  Business  Valuation:  FTE  approach Exercise In  year  1,  AMC  will  earn  $2000  before  interest  and  taxes. The  market  expects  these   earnings  to  grow  at  a  rate  of  3%  per  year. The  firm  will  make  no  net  investments  (i. e. ,   g g %p y ( , capital  expenditures  will  equal  depreciation)  or  changes  to  net  working  capital. Assume  that  the  corporate  tax  rate  equals  40%. Right  now,  the  firm  has  $5000  in  risk? free  debt. It  plans  to  keep  a  constant  ratio  of  debt  to  equity  every  year,  so  that  on   average  the  debt  will  also  grow  by  3%  per  year. Suppose  the  risk? free  rate  equals  5%,   and  the  expected  return  on  the  market  equals  11%. The  asset  beta  for  this  industry  is   1. 11.  ©Ã‚  2011  Dr. Tanja  Kirn  Ã¢â‚¬â€œ University  of  Liechtenstein  Ã¢â‚¬â€œ Vaduz 3 The  Economics  of  Taxation Taxation  and  Business  Valuation:  FTE  approach Questions a. If  AMC  were  an  all? equity  (unlevered)  firm,  what  would  its  market  value  be? b. Assuming  the  debt  is  fairly  priced,  what  is  the  amount  of  interest  AMC  will  pay  next  year? If  AMC’s   debt  is  expected  to  grow  by  3%  per  year,  at  what  rate  are  its  interest  payments  expected  to  grow? c. Even  though  AMC’s  debt  is  riskless  (the  firm  will  not  default),  the  future  growth  of  AMC’s  debt  is   uncertain,  so  the  exact  amount  of  the  future  interest  payments  is  risky. Assuming  the  future  interest

Journey Into The Unknown English Literature Essay

It was about 15 old ages ago in 1995 when I foremost discovered that my married woman was holding serious issues with memory. We had gone to see friends in North Carolina when I realized that Betty had forgotten to pack a batch of the points we needed – toothpaste, towels, lens solution, formal wear for the party we would be go toing. I thought nil of it then- she likely left the bag at place incorporating all those points. A few hebdomads subsequently when we had returned back place I caught her inquiring me the same inquiry twice- Did we pay the electric measure? I answered her twice with some vacillation. Two months subsequently in June, her friends and household threw her a surprise 58th birthday party at our place. She looked truly surprised when I led her into the house full of thirstily expecting invitees. She had smiled up at me and had proceeded to recognize everyone coming up to her. The party was in full swing when I had passed by the kitchen for more beers when I caught her inquiring my female parent whose bar was sitting on her dining room tabular array. My female parent believing it was a gag laughed. Not three proceedingss later she came up to me and asked the same inquiry. That scared me to the bone because she was dead serious. Subsequently that dark as were turning in for bed she commented that she had non realized her birthday had arrived- it had merely slipped her head. I was still staggering from the incident earlier and began to acquire more frightened. Was she merely so busy at work and with the combination of aging that led her to bury that her birthday was today? These inquiries unsettled me and that dark was when I foremost started holding serious ideas about taking her to a physician. Betty worked as a secretary replying calls and scheduling clients for a local watering place salon. She had worked there for some 20 old ages while I worked in the building concern. I knew her to be a really organized person who was ever on top of things. She was frequently the 1 who would retrieve to name the aunts and uncles and cousins when their day of remembrances or birthdays had arrived. She had grown up as the younger of two kids in Edison, New Jersey. I had known her since I was in junior high and we began dating in high school, frequently hanging out with friends at the local Burger topographic point in near our school. She had finished high school when we had decided to acquire married and get down our life together. I did n't cognize that my universe Lashkar-e-Taiba alone my married woman ‘s would shortly be turned upside down. Betty was known to maintain this small contriver with her that contained all the of import day of the months and events. Had she merely bury to pencil in her birthday in her calendar? Does one even necessitate to make that for their ain birthday? I tired to disregard these ideas but slumber was non easy to come by that dark. We decided to travel to the physician ‘s for our everyday visit the following month. Once I was at that place I had told the physician outside the room that Betty seemed to be holding trouble retrieving things. He said he wold expression into it. By the terminal of the visit 20 proceedingss subsequently, it was decided that Betty was likely covering with depression. This came as a flooring diagnosing to the both of us. Nevertheless, I convinced her to get down the medicine recommended to her by the physician. For months she was on an anti-depressant and she did non detect a alteration. I nevertheless, noticed drastic changes- but non for the better. Betty had received a call from work one eventide. Unbeknownst to me, Betty had failed to schedule in clients into the work calendar for a few months to the point where clients would demo up for their assignment they made over the phone merely to be told that there was no record of it. Betty must hold spoken to the adult females over the phone and confirmed unfastened times but failed to come in them into the system. It happened plenty times to justify her losing her occupation. She seemed baffled and denied anything of the kind. However much I wanted to believe her I began holding uncertainties about her abilities or deficiency thereof. I reexperienced the same sinking feeling I felt the twelvemonth earlier at the surprise birthday party. Is she losing it? I decided to name our boy that dark and inquire him to see us sometime and that I had something I wanted to discourse with him. He and his household came to see two months subsequently. I relayed everything traveling on with his female parent to him and he sat there and listened to it all. He did non experience that his female parent was depressed. He thought it was old age but encouraged me to take her to another physician, possibly a brain doctor. He did detect a alteration in her over the past twelvemonth and had besides caught her inquiring him the same inquiry multiple times during his visit, twosome of times even burying her one twelvemonth old grandson ‘s name. I was convinced and took her to see a brain doctor. It was at this visit with him, that I eventually received some replies that made sense. After some trials, he had given Betty a diagnosing of early-onset Alzheimer ‘s. I was both in denial and relieved at the same clip. What he described to me made sense and I could see it in the daily activities that Betty went through. But I could non penetrate why it had to be her and why now at this clip. She was quickly started on medicine. With her d iagnosing came my transmutation from a comrade to a full clip health professional where it became my bend to take attention of her. The physical and emotional toll of being a full-time health professional was overpowering. I was inundated with the day-to-day jobs of cookery, cleansing, shopping for the food markets, paying the measures, and making the laundry- all the things that Betty one time was in charge of and did with such evident easiness. Over clip I realized the importance and critical function in my saneness of making out and inquiring others for aid. Friends and household became line of lifes when I needed to take a interruption from caregiving. They would watch her and maintain her company while I would take a dark off to pass clip with friends and unwind. The physician every bit good has been a enormous support and proctors her on a regular basis. The most of import lesson John has realized is that taking attention of a loved 1 with Alzheimer ‘s does non necessitate to be a lone and only journey. Although Betty continues to smile, it is non the same smiling they used to portion when they were younger. Although she engages in conversation with him, it is non the same as before. While he may hold lost some of Betty he one time knew, he has discovered some new qualities in his married woman throughout this journey that still motivate him to care for her merely the same. And for him it is so a journey into the unknown with his married woman by his side and support of household and friends.

Free Essays on Whats Being Done To Service

What’s Being Done with the Service? By Derek Raposa Table of Contents Introduction†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.2 What are Companies Providing to Ensure Employee Satisfaction?†¦Ã¢â‚¬ ¦.†¦Ã¢â‚¬ ¦.3,4 Does Employee Training Play a Role in Customer Satisfaction?†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..†¦.4,5 What Does Southwest Provide Its Customers?†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.....8,9 What Does American Offer Better than Southwest? †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..9,10 What About the Internet?†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦11,12 What’s In Store for the Future?†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.12,13 Conclusion†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.13 How to Contact Each Airline†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦15,16 Comics†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦17 Table of Illustrations†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..18 Index†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦19 Introduction Airlines have increasingly had to maintain good customer relations due to competition. What are certain companies such as Southwest and American airlines doing to ensure quality customer service on their flights? The purpose of this study is to examine how these two airline companies meet consumer needs, in order, to stay competitive. The airlines’ customer service will be evaluated on customer relation’s skills, types of complementary services, promotional incentives, and airline dependability. What are Companies Providing to Ensure Employee Satisfaction? The main idea that comes to mind when speaking to employees at southwest is there continued commitment to employee satisfa... Free Essays on Whats Being Done To Service Free Essays on Whats Being Done To Service What’s Being Done with the Service? By Derek Raposa Table of Contents Introduction†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.2 What are Companies Providing to Ensure Employee Satisfaction?†¦Ã¢â‚¬ ¦.†¦Ã¢â‚¬ ¦.3,4 Does Employee Training Play a Role in Customer Satisfaction?†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..†¦.4,5 What Does Southwest Provide Its Customers?†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.....8,9 What Does American Offer Better than Southwest? †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..9,10 What About the Internet?†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦11,12 What’s In Store for the Future?†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.12,13 Conclusion†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.13 How to Contact Each Airline†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦15,16 Comics†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦17 Table of Illustrations†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..18 Index†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦19 Introduction Airlines have increasingly had to maintain good customer relations due to competition. What are certain companies such as Southwest and American airlines doing to ensure quality customer service on their flights? The purpose of this study is to examine how these two airline companies meet consumer needs, in order, to stay competitive. The airlines’ customer service will be evaluated on customer relation’s skills, types of complementary services, promotional incentives, and airline dependability. What are Companies Providing to Ensure Employee Satisfaction? The main idea that comes to mind when speaking to employees at southwest is there continued commitment to employee satisfa...

24 Simple Rules That Every Teacher Should Live By

24 Simple Rules That Every Teacher Should Live By One of the best things about teaching is that there is not an exact blueprint for success. In general, no two teachers are alike. Each has their own teaching style and classroom management routines. But while there is no blueprint for teaching, there is a certain code that teachers must live by if they want to be successful. The following list is a general set of rules that every teacher should live by. These rules encompass all facets of teaching, both inside and outside of the classroom.   Rules for Teachers Always do what you believe to be best for your students. They should always be your number one priority. Think, how does this benefit my students? If that question is difficult to answer, you may want to reconsider.Focus on establishing meaningful, cooperative relationships. Building strong relationships with your students, peers, administrators, and parents will ultimately make your job easier.Never bring your personal problems or issues into the classroom. Leave them at home. Your students should never know when something at home is bothering you.Be open and willing to learn at all times. Teaching is a journey that will provide many opportunities to learn. You should strive to improve your teaching each and every day, even when youve been in the classroom for years.Always be fair and consistent. Your students are always watching to make sure you are doing this. You will undermine your own authority if they believe you are playing favorites.Parents are the cornerstone of a great edu cation, and as such, teachers must do their part to engage even the most reluctant parents in the learning process. Provide plenty of opportunities for parents  to become involved  and encourage them to do so. A teacher must never put herself or himself  in a compromising situation. Teachers must always be aware of their situation and never allow themselves to be vulnerable. They must maintain self-control at all times, protecting themselves and their reputation.Respect the decisions of administrators and understand that they have many responsibilities.  Teachers must have a great working relationship with their administrator but respect the fact that their time is valuable.Take the time to get to know your students. Find out what they like to do and include their interests in your lessons. Establish a rapport and connection with them, and you will find that engaging them in your lessons becomes easier.Establish rules, expectations, and procedures beginning on the first day of school.  Hold your students accountable for their actions. You do not have to be a dictator, but you do need to be firm, fair, and consistent. Keep in mind that you are not there to be their friend. Your studen ts need to know that you are in always in charge. Always be willing to listen to others, including your students, and take their feedback into account. You can learn the most when you are willing to take the time to hear what others are saying. Be open-minded and willing to take their advice.Own your mistakes. Teachers are not perfect, and it doesnt help your students to pretend that you are. Instead, set the example by owning your mistakes and showing your students that mistakes can lead to learning opportunities.Work cooperatively with other teachers. Always be willing to take another teacher’s advice. Likewise, share your best practices with other teachers.Find time outside of school to decompress. Every teacher should have some sort of hobby or interest that can help them escape the daily grind of school.  Always be willing to adapt and change. Teaching is always changing. There is always something newer and better to try.  Try to embrace change instead of resisting it.Teachers must be flexible. Some of the best momen ts in teaching are born out of spontaneity. Take advantage of those teachable moments. Be willing to change your plans when another opportunity presents itself. Be your students’ biggest cheerleader. Never tell them that they cannot do something. Help them accomplish their goals by setting them on the correct path and nudging them in the right direction when they go astray.Protect your students at all cost. Always be aware of your surroundings and ensure that your students are safe and secure at all times. Practice safety procedures within your classroom at all times and never allow students to engage in reckless behavior.Take a cue from the boy scouts and always be prepared! Preparation may not necessarily guarantee success, but the lack of preparation will almost certainly ensure failure. Teachers must put in the necessary time to create meaningful lessons that engage students.Have fun! If you enjoy your work, your students will notice and they will have a more enjoyable experience as well.Never purposely embarrass or put down a student in front of their peers. If you need to discipline or correct a student, do so privately in the c onfines of the hallway or after class. As a teacher, you need your students to trust and respect you. Give your students a reason to do this. Go the extra mile when you can. A lot of teachers volunteer their time for things like tutoring struggling students or sponsor a group or activity. These small actions mean a lot to your students.Never fall behind in grading and recording. It can be an overwhelming and almost impossible endeavor to try and catch up. Instead, set a goal to grade and return every paper within a two- to three- day period. This not only makes your job easier but also provides students with more relevant and timely feedback.Always be aware of and adhere to local policies and procedures. If you are not sure about something, it is better to ask and be sure than it is to make a costly mistake. As a teacher, you are responsible for ensuring that your students are following them as well.